All sympathetic and parasympathetic preganglionic neurons release Acetylcholine from BIO 225 at Marian University ... What is the major control center for both the sympathetic and parasympathetic divisions of the Autonomic Nervous System. These axon terminals are the only axon terminals to release norepinephrine. at the synapses of all autonomic ganglia). At all parasympathetic postganglionic nerve endings. Postganglionic sympathetic neurons. Both sympathetic and parasympathetic preganglionic neurons are cholinergic, meaning they release acetylcholine (Ach) at the synapse in the ganglion. Muscarinic acetylcholine receptors are also present and distributed throughout the local nervous system, in post-synaptic and pre-synaptic positions. The parasympathetic system is responsible for vegetative functions, uses the neurotransmitter acetylcholine, and has short postsynaptic nerves located near or on the organs they innervate. There is also some evidence for postsynaptic receptors on sympathetic neurons allowing the parasympathetic nervous system to inhibit sympathetic effects. The neurotranmitter in the ganglia of both parasympathetic and sympathetic nervous systems is acetylcholine, which activates a unique “nicotinic ganglionic” receptor on the postganglionic membrane that has a different subunit composition compared to nicotinic receptors expressed in the neuromuscular junction. The axon terminals of all (or almost all) of these neurons release acetylcholine into their synaptic junctions. Sympathetic vs. Parasympathetic: It’s All about Balance The sympathetic nervous system interacts with the hypothalamus–pituitary–adrenal (HPA) axis to control the body’s stress response. At the end of the preganglionic fibers supplying the adrenal medulla. In the parasympathetic system, postganglionic neurons are also cholinergic. The parasympathetic nervous system resets organ function after the sympathetic nervous system is activated (the common adrenaline dump you feel after a ‘fight-or-flight’ event). https://diffzi.com/parasympathetic-vs-sympathetic-nervous-system It is the chief neurotransmitter of the parasympathetic nervous system, which contracts smooth muscles, dilates blood vessels, increases bodily secretions, and slows heart rate. However in the sympathetic system, postganglionic are not all the same. The parasympathetic nervous system resets organ function after the sympathetic nervous system is activated (the common adrenaline dump you feel after a ‘fight-or-flight’ event). Acetylcholine, transmitter substance of nerve impulses within the central and peripheral nervous systems. 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